Job Erasmus University Rotterdam - (Senior) Lecturer Mathematics and Computational Science

Job description

The primary tasks of the (Senior) Lecturer are to co-develop, carry out and coordinate academic courses in the fields of Mathematics and Computational Science for the curriculum of Erasmus University College. Secondarily the (Senior) Lecturer will act as a tutor in various courses in the curriculum that are based on the didactic format of problem-based learning, may be called upon to assist in the guidance of small groups for lab skills and will supervise Capstone projects of students.

Requirements

• You hold a PhD in a relevant field of research (Mathematics, Informatics or Physics);
• You have relevant teaching experience;
• You have excellent communication skills and you are highly proficient in the English language (at least C1 level in the CEFR, C2 level is preferred);
• You are looking forward to become a proactive member of a stimulating academic community that is the hallmark of an university college;
• We explicitly invite international candidates to apply for this vacancy.

Conditions of employment

The vacant position is fulltime (1.0 fte). The new (Senior) Lecturer is invited to join Erasmus University College as soon as possible and preferably no later than 1 July 2015. Contracts will initially be running for a period of one year, with a possible extension.
The teaching load of the (Senior) Lecturer will be 100%. After one year in position and provided that prerequisites (PhD, strong track record and/or clear potential as a researcher) are met, the (Senior) Lecturer may apply within EUC for a research voucher. When granted, the research voucher will allow the (Senior) Lecturer to free up to 20% of their workload for a period of up to two years to focus on research activities. Continuation of such a research voucher is dependent on the ability of the (Senior) Lecturer to acquire sufficient external funding.
The conditions of employment comply with the ‘CAO Nederlandse Universiteiten/Collective Agreement Netherlands Universities (CAO NU)’. Salary is subject to know-how and experience and will be within salary scale 10 (for a Lecturer, starting at 2,476 Euro gross salary per month) or salary scale 11 (for a Senior Lecturer, starting at 3,324 Euro gross salary per month). Starting salaries tend to be near the lower end of the scale.
Erasmus University has attractive employment conditions, which include a holiday allowance of 8.0%, an end-of-year bonus of 8.3% and up to 41 annual vacation days.

Contract type: Temporary, one year

Organisation

Erasmus University Rotterdam

The expertise of Erasmus University Rotterdam (EUR) is concentrated in the fields of  Business Administration,  Economics, Medicine and Health Sciences, Law, Social Sciences, History, Culture and Communication, and Philosophy. In addition to the initial degree programmes and scientific research, the University offers specific postgraduate study programmes and courses. Erasmus University has around 25,000 students and some 2,700 staff members.

Department

EUC

Erasmus University College is the EUR’s internationally orientated and selective undergraduate college, that offers a bachelor’s degree programme in Liberal Arts and Sciences based on intensive multi-discipline education. The college and its city campus are located in the centre of metropolitan Rotterdam. The residential character of the college attributes to a safe academic community in which its students live and study together. Erasmus University College offers four Majors: Life Sciences, Humanities, Social Sciences, and Economics & Business.

Additional information

For more information about the Erasmus University College, please visit the website www.eur.nl/euc. For more information about the vacancy applicants should contact Dr. Kees Vink, Associate Professor and Head of Life Sciences (vink@euc.eur.nl).
Applicants should send an electronic copy of their letter of interest, curriculum vitae, and names of two referees to working@euc.eur.nl. The deadline for applications is Sunday 23 May 2015. Screening will start immediately and continue until the position is filled. Selected candidates will be invited to an interview with a selection committee.

https://www.academictransfer.com/employer/EUR/vacancy/27916/lang/en/ 

Postdoctoral Researcher or Assistant Professor Mathematics Leiden University - Leiden — AcademicTransfer

Postdoctoral Researcher or Assistant Professor Mathematics Leiden University - Leiden — AcademicTransfer .

Job description

This
is a broad search that is open to outstanding applicants from all areas
of mathematics, preferably related to the research areas represented at
the institute. These are Algebra, Geometry, Number Theory, Statistics,
Analysis and Probability Theory. Applicants with a different academic
focus who can explain their added value for the institute are welcome to
apply. The nature of the position will depend on experience and
qualifications of the candidate.

Requirements

• Hold a Ph.D. in mathematics;
• Have demonstrated potential for excellence in research;
• Are able and willing to effectively teach graduate and undergraduate level courses;
• Have an energetic personality and good communication skills;
• Are willing to contribute to the organization of the institute;
• Are eager to join in national/international research collaborations;
• Are able to raise national and international research funds.

Conditions of employment

We
offer a full-time, temporary position of Postdoctoral Researcher or
Assistant Professor. Details of the positions offered will depend on
experience and qualifications of the candidate. The salary will be pay
scale 10 or 11 in accordance with the Collective Labour Agreement for
Dutch Universities (cao). Salary range from € 2.476,- to € 4.551,- gross
per month.

The University aims to employ more women in areas
where they are underrepresented. Women are therefore especially invited
to apply.

Leiden University offers an attractive benefits package
with additional holiday (8%) and end-of-year bonuses (8.3 %), training
and career development and paid parental leave. Our individual choices
model gives you some freedom to assemble your own set of terms and
conditions. Candidates from outside the Netherlands may be eligible for a
substantial tax break.

Organisation

Leiden University

Leiden
is a typical university city, hosting the oldest university in the
Netherlands (1575). The University permeates the local surroundings;
University premises are scattered throughout the city, and the students
who live and study in Leiden give the city its relaxed yet vibrant
atmosphere.

Leiden University is one of Europe's foremost research
universities. This prominent position gives our graduates a leading
edge in applying for academic posts and for functions outside academia.

Department

Faculty of Science, Mathematical Institute

The
Mathematical Institute is one of the institutes in the Faculty of
Science of Leiden University. The Faculty of Science has more than 2,600
students enrolled in 8 bachelor and 11 master programs. Working at the
Faculty of Science means being part of a dynamic scientific community
that sets high standards for its students, staff and support staff
alike. The Faculty is known for its friendly and team-spirited
atmosphere, which promotes mutual exchange of knowledge. For more
information, see www.science.leidenuniv.nl.

The
Mathematical Institute is responsible for the mathematical research and
education within the Faculty of Science. Currently, there are 120 staff
members and 330 bachelor- and master students from all over the world. A
diverse mix of people from different academic and cultural backgrounds
characterizes the institute. For more information, see www.math.leidenuniv.nl/en/home/.

Additional information

For more information, please contact the coordinator of the Mathematisch Instituut, Ms Kathelijne Smits (e-mail: smitskgm@math.leidenuniv.nl , telephone: 0031 (0)71 527 7111).

Information about the Faculty of Science can be found at www.science.leidenuniv.nl/index.php/english/ and about Leiden University at www.vacancies.leiden.edu/.

VACANCY: PhD student SpySpot: Visualization of Advanced Persistent Threats

PhD student SpySpot: Visualization of Advanced Persistent Threats

Specifications - (explanation)

Function types	PhD positions
Scientific fields	Engineering
Hours	36.0 - 40.0 hours per week
Education	University Graduate
Job number	V32.1786
Translations	nl en
About employer	Eindhoven University of Technology (TU/e)
Short link	www.academictransfer.com/19124

Job description

Project Description: Cyber-attacks have grown in number and sophistication, achieving unprecedented success in reaching their targets. Advanced Persistent Threats (APTs) such as data exfiltration attacks are both dangerous and difficult to detect. These targeted and stealthy attacks using specifically developed malware circumvent classical detection systems based on signatures or statistical anomalies in network traffic. Only by looking in detail at the actual content of communication would it be possible to detect APTs. A method is thus needed to analyse the huge amount of data involved in an effective way.
SpySpot proposes a solution which combines deep packet analysis with visualization of the analysis results enabling an end user to easily spot anomalies created by APTS like digital espionage. In the deep packet analysis the meaning of communication is recovered using protocol syntax and semantics, abstraction brings additional structure to this meaning and anomaly detection finds patterns deviating from the norm. While automated analysis is needed to manage the huge amount of data, no automatic method can match the ability of the human mind in recognizing deviations and evaluating these. The analysis will thus support visualization of results for human-based evaluation and be able to take into account feedback on the discovered anomalies, such as discarding harmless ones in future traffic.
As a PhD student your tasks concern the following activities:

• carry out research within the project, in cooperation with the other parties involved;
• report on the results in papers and conference contributions;
• finishing a PhD thesis in four years;
• a small contribution to the teaching activities of the Visualization group may be asked.

Requirements

Requirements:We are looking for a candidate who meets the following requirements:

• a Master degree in Computer Science, Mathematics, or closely related discipline;
• a strong interest in information visualization, human computer interaction, and security;
• excellent analytic, creative, and implementation skills;
• ability to work in a team, cooperate both with academic and industrial partners;
• fluent in spoken and written English.

Conditions of employment

Appointment and salary:We offer:

• a full-time temporary appointment for a period of 4 years, with an intermediate evaluation after 9 months;
• a gross salary of € 2,062 per month in the first year increasing up to € 2,638 per month in the fourth year;
• a broad package of fringe benefits (e.g. excellent technical infrastructure, the possibility of child daycare and excellent sport facilities).

Additional information

Information:

• For more information about the project, please contact prof.dr.ir. J.J. van Wijk, e-mail: J.J.v.Wijk@tue.nl .
• For information about employment conditions, please contact mr. C. Kuiters HR-advisor TU/e, e-mail: pzwin@tue.nl.

Application:The application should consist of the following parts:

• a cover letter explaining your motivation and qualifications for the position;
• a detailed Curriculum Vitae (and if applicable a list of publications);
• contact information of two references;
• copies of diplomas (including list of courses and grades);
• proof of English language skills (if applicable).

 Deadline for application: January 31st, 2014.
!!Submit your application using the “APPLY NOW” button!! ---> GO to this website: https://www.academictransfer.com/employer/TUE/vacancy/19124/lang/en/

Job Erasmus MC - PhD Student for the department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics - Phenotyping of 3D facial morphology: from basic methodology to clinical application

PhD Student for the department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics - Phenotyping of 3D facial morphology: from basic methodology to clinical application

Specifications - (explanation)

Location	Rotterdam, 3015 CE, The Netherlands
Function types	PhD positions, Research, Development, Innovation
Scientific fields	Health
Hours	36.0 hours per week
Salary	maximum € 3605
Education	University Graduate
Job number	42.10.12.THZ
Translations	en

Apply for this job within 18 days

Job description

Project leaders:

Prof.Dr. Eppo Wolvius, Department of Oral & Maxillofacial Surgery, Special Dental Care, and Orthodontics, Erasmus MC;

Prof.Dr. Manfred Kayser, Department of Forensic Molecular Biology, Erasmus MC.

In collaboration with:

Dr. Stefan Böhringer, Department of Medical Statistics and Bioinformatics, LUMC;

Prof.Dr. Wiro Niessen, Biomedical Imaging Group Rotterdam (BIGR), Erasmus MC.

The human face is an intriguing human trait that has an important role in almost every aspect of life including disease. Both biological and environmental factors contribute to normal and pathological variation of the human face. In this project, new bioinformatics methodology will be developed to automatically extract anatomic features from facial 3D data. Using modern statistical techniques, these data will be used to answer clinical and basic science questions. These questions include discrimination of certain conditions or the quantification of the influence of environmental and/or genetic factors on facial development. This project combines exciting aspects of computer vision, modern bioinformatics and statistical techniques in a close embedding with life sciences and clinical practice. This project will build upon existing research experiences in facial phenotyping and its biological determinants. A recent publication can be found at: www.plosgenetics.org/[...].

Requirements

We are looking for a highly motivated MSc student who has a strong background in mathematics, physics, (biomedical) engineering, or computer science. Programming experience in a procedural language is required (Preferably Matlab or C, C++, Java). Experience in bio-image analysis is an advantage. You are independent but at the same time you can work in a multidisciplinary team. You display a well-structured working style, you have good communication skills and you have an excellent command of the English language, both oral and in writing.

Conditions of employment

We offer you a temporary employment for a period of four years. Enrolment in the postgraduate Advanced School for Computing and Imaging-TU Delft is planned. The gross monthly salary amounts, based on education en previous work experience, a maximum of € 3.605,- (scale 9), based on a 36 hour working week. In addition, we offer you an end of year bonus, a holiday gratification and personal budget for your personal development. The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

Contract type: Temporary, four years

Organisation

Erasmus MC

Erasmus MC inspires and is challenging. You create your own opportunities in this University Medical Center. Whether it concerns learning and work or work and learning/continued learning. Each and every day our enthusiastic staff devote themselves to excellent, dedicated patient care, pioneering medical research and valued education. A conscious choice for work that matters, both nationally and internationally, at the heart of our multicultural home base ofRotterdam. Where attention to individual staff member comes naturally. Working from the heart. Together with people, for people: ‘patient-centered care’!

Department

Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics

Together with patient data collected at the department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, the cohort study ‘Generation R’, which investigates growth and development of 10.000 children from Rotterdam (www.generationr.nl/), offers a unique chance to broaden our knowledge of facial development by providing detailed facial 3D image data on an extensive data set.

Additional information

For more information on this vacancy, please contact Prof.Dr. Eppo B. Wolvius, telephone (+31)(0) 10 703 4138, e-mail: e.wolvius@erasmusmc.nl, or Prof.Dr. Manfred Kayser, telephone (+31)(0) 10 703 8073, e-mail: m.kayser@erasmusmc.nl. For additional information please contact the HR department, telephone (+31)(0) 10 703 4433.

More information about employer Erasmus MC (University Medical Center Rotterdam) on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/15919

VACANCY: Postdoc determining radiation dose distribution for radiotherapy

Job Erasmus MC - Postdoc for the department of Radiotherapy - Mathematical Optimization of Cancer Treatment

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Postdoc for the department of Radiotherapy - Mathematical Optimization of Cancer Treatment

Specifications - (explanation)

Location	Rotterdam, 3015 CE, The Netherlands
Function types	Postdoc positions, Research, Development, Innovation
Scientific fields	Health
Hours	36.0 hours per week
Education	Doctorate
Job number	27.03.12.TDdH
Translations	en

Apply for this job within 31 days

Job description

Approximately 50% of cancer patients is treated with radiotherapy. Success of a radiation treatment is largely determined by the quality of the delivered dose distribution. Doses should be very high in the tumor and as low as possible in surrounding healthy tissues, especially in vital radiation sensitive organs. Development of algorithms and procedures for design of individualized irradiation strategies (treatment plans) is a key research line of the department. Optimization of the patient’s dose distribution is a complex, non-convex and discrete mathematical problem with multiple objectives and constraints, and a patient anatomy that may change during the fractionated therapy. Not only the quality of the final dose distribution is important, but also optimization time, speed of daily dose delivery and required human interaction and workload. The selected candidate will participate in these investigations.

Requirements

• PhD in operations research, numerical mathematics, or other relevant field;
• Excellent programming skills (Python, C++, Matlab) for prototyping;
• Ambitious and eager to take initiative;
• Creative and excellent analytical skills;
• Ability to work in a multi-disciplinary team.

Conditions of employment

We offer a full-time position for a period of 3 years in an exciting working environment, aiming at improvement of patient care. The salary will depend on relevant experience and the job conditions are according to the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

Contract type: Temporary, 3 years

Organisation

Erasmus MC

Erasmus MC inspires and is challenging. You create your own opportunities in this University Medical Center. Whether it concerns learning and work or work and learning/continued learning. Each and every day our enthusiastic staff devote themselves to excellent, dedicated patient care, pioneering medical research and valued education. A conscious choice for work that matters, both nationally and internationally, at the heart of our multicultural home base ofRotterdam. Where attention to individual staff member comes naturally. Working from the heart. Together with people, for people: ‘patient-centered care’!

Department

Radiotherapy

The Erasmus MC-Daniel den Hoed Cancer Center encompasses one of the largest radiation oncology departments in Europe treating 5000 patients per year. The departement has a wide-ranged and internationally renowned research program. Physics is of major importance in the program and a large part of the 50 employees of the Medical Physics division is involved in research projects. The department is equipped with state-of-the-art technologies and an extensive R&D software framework. Apart from computer optimization, image-guided and adaptive treatment, robotic treatment, stereotactic treatment, and proton therapy are among the main research lines. The department participates in the Holland Particle Therapy Center (HollandPTC) project. Research is embedded in multi-disciplinary teams, consisting of radiation oncologists, (medical) physicists, radiation technologists, mathematicians, and computer scientists.

Additional information

For more information, please contact Prof.dr. B.J.M. Heijmen, head of physics, telephone (+31) (0) 10 7041304, e-mail: b.heijmen@erasmusmc.nl, Ir. S. Breedveld, project leader, telephone (+31) (0) 10 7042693, e-mail: s.breedveld@erasmusmc.nl, or Drs. M.J. de Bruin, head of operations, telephone (+31) (0) 10 7041480, e-mail: m.j.debruin@erasmusmc.nl. More information on the R&D program can be found at: www.ncbi.nlm.nih.gov/pubmed?term=heijmen%20b*.

More information about employer Erasmus MC (University Medical Center Rotterdam) on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/14749

VACANCY: Technical Programme Manager in Visualization (1,0 fte)

Specifications - (explanation)

Location	Groningen
Function types	IT
Hours	38.0 hours per week
Salary	maximum € 4374
Education	Higher Professional Education +
Job number	212147
Translations	en

Apply for this job within 13 days

Job description

As part of the Target project the Donald Smits Centre for Information Technology (CIT) of the University of Groningen seeks an expert in scientific data visualization. The successful candidate will collaborate with the existing High Performance Computing and Visualization group in the CIT, to further expand the use of the existing 3D visualization theatre. New uses will include: the visualization of large datasets from astronomy, visualisation of medical datasets (in collaboration with Target Holding BV and the scientific Visualization and Computer Graphics Group of the university).
The successful candidate will participate in the development of the Infoversum project, including research into novel methods of data presentation. They will be expected to assist in the selection of suitable technology solutions for both projection and software systems. Moreover, they will take a leading role in the production of new material for the Infoversum.

Requirements

- a Bachelor level or higher degree in a relevant subject such as Multimedia Production
- significant experience in data visualization in several fields e.g. astronomy, geophysics, climate science
- proven experience in production of advanced multi-media materials for dome and/or 3D theatres
- detailed knowledge of one or more commercial systems used for dome visualization (e.g. E&S Digistar 4 or SCISS Uniview Theater/Producer)
- excellent communication skills, particularly when addressing expert audiences.

Conditions of employment

The University of Groningen offers a salary dependent on qualifications and work experience up to a maximum of € 4,374 gross a month (scale 11) based on a full-time position. It is a temporary assignment starting as soon as possible and ending December 2014.

Please pronounce the names and contact information of at least two references in your curriculum vitae.

Application
Interested candidates are requested to submit a letter of motivation, a curriculum vitae (including 2 references) before 17 August 2012 by means of the application form.

Acquisition is not appreciated.

Organisation

Faculty of Mathematics and Natural Sciences

TARGET undertakes R&D of massive data handling and information systems for astronomical surveys such as ESA's Euclid mission, ASTRON's Lofar radio telescope, ESO's OmegaCAM optical wide-field imager and Muse spectrometer. Non-astronomical projects include handwritten text recognition and the medical Lifelines project, registering the medical records and genome profiles of 165,000 patients over a 30 year period.
TARGET provides a regional knowledge cluster initiated by the Kapteyn Astronomical Institute, the University Computing Center, Artificial Intelligence Department, University Medical Center, ASTRON and various companies (including IBM and Oracle). TARGET connects distributed information systems to storage systems and compute grids ranging from Linux clusters, IBM Blue Gene/P to the European networks of EGEE GRID, EURO-VO and Astro-WISE.
Target initiates a visualization programme on "big-data" both for discovery, decision taking and dissemination purposes, employing the Universities 25 seats 3D-theatre and the Cave and bridging this to a new Target project, the Infoversum Dome Theatre. This state of the art, full-dome digital theatre is due to open in 2013. It will be located in the centre of Groningen and seat 265 people. The Infoversum will be used for a mixed programme, including scientific discovery, outreach, public relations, "infotainment" and business-to-business events.

Additional information

Prof. Edwin Valentijn
valentyn@astro.rug.nl

Dr O.R. Williams
o.r.williams@rug.nl

TARGET

More information about employer University of Groningen on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/15108

Found here: http://www.academictransfer.com/employer/RUG/vacancy/15108/lang/en/

VACANCY PhD students in Big Data Analytics

PhD students in Big Data Analytics for CWI (Centrum Wiskunde & Informatica). The research group "Database Architectures" in the cluster "Information Systems" has vacancies for three talented PhD students.

Specifications - (explanation)

Location	Amsterdam, the Netherlands
Function types	PhD positions
Scientific fields	Economics, Mathematics
Hours	40.0 hours per week
Salary	€ 2057 - € 2636
Education	University Graduate
Job number	AT PhD Big Data Analytics
Translations	nl en

Apply for this job within 6 days

Job description

The research group "Database Architectures" in the cluster "Information Systems" has vacancies for three talented PhD students in Big Data Analytics.
The positions are in the broad area of big data analytics to enable robust and scalable big data analytics. Research topics are in novel query processing, (adaptive) indexing and optimization techniques, and bridging the gap between application programming and big data storage.
One of these vacancies is in the context of a collaboration project with Actian Vectorwise, while the other two are related to the Dutch national research program COMMIT.
An internship at one of the partnering database research labs world-wide is considered part of the PhD track.

Requirements

Candidates are required to have a master degree in computer science (or a five year diploma). Specialization is needed in databases, distributed systems, software engineering mathematics, or related fields. Preferable qualifications for candidates include proven research talent, system programming skills (C/C++), practical experience with using and implementing database systems, and software development in a team.
Candidates are expected to have an excellent command of English, and good academic writing and presentation skills.

Conditions of employment

The terms of employment are in accordance with the Dutch Collective Labor Agreement for Research Institutes ("CAO-onderzoeksinstellingen"). Moreover CWI offers attractive working conditions, including flexible scheduling and help with housing for expat employees. CWI also offers excellent and flexible terms of employment, including an employee pension fund.
The gross monthly salary, for an employee on a full time basis, is €2,057 during the first year and increases to €2,636 over the four year period.

Contract type: Temporary, 4 years.

Organisation

Centrum Wiskunde & Informatica (CWI)

Founded in 1946, CWI is the national research center for mathematics and computer science in the Netherlands. More than 170 full professors have come from CWI, of whom 120 still are active. CWI's strength is the discovery and development of new ideas, and the transfer of knowledge to academia and to Dutch and European industry. This results in importance for our economy, from payment systems and cryptography to telecommunication and the stock market, from public transport and internet to water management and meteorology.
An international network
With its 55 permanent research staff, 40 postdocs and 65 PhD students, CWI lies at the heart of European research in mathematics and computer science. Researchers at CWI are able to fully concentrate their efforts on their scientific work, and to build an international network of peers. More than half of the permanent research staff maintains close contact with universities as part-time professors. The personal and institutional research networks strengthen CWI's positions and serve as a magnet for attracting talent. The CWI researchers come from more than 25 countries world-wide.

Department

Database Architectures

The Database Architectures group at CWI is one of the world-wide leading groups in system-oriented database research. Among other honours, it received the 10-year best paper award at VLDB 2009 for their pioneering research on hardware-aware database technology and the column-store model, both the 2011 ACM SIGMOD Jim Gray Dissertation award and 2011 ERCIM Cor Baayen award for the database cracking work, as well as the VLDB 2011 Challenges & Visions Track best paper award for their visionary work on innovative database architectures to support big data analytics and data-intensive scientific discovery.
The group has a unique methodology that combines fundamental database research with active participation of all group members in database engineering, centred around the open-source analytical database system MonetDB.  

Additional information

Additional information can be obtained from Dr. Stefan Manegold, email stefan.manegold@cwi.nl.
Please send your application before 15 July 2012.

Applications should include a detailed CV, a motivation letter, a list of your M.SC. courses and grades, a copy of your master thesis, and preferably a list of publications.
Additional information about working at the CWI can be seen at the video “A Fundamental Difference”: www.cwi.nl/general/movies-about-cwi

More information about employer Centrum Wiskunde en Informatica (CWI) on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/14581

Found here: http://www.academictransfer.com/employer/CWI/vacancy/14581/lang/en/

VACANCY: Postdocs PhDs: Computational Analysis of NGS data

06-21-2012

Vacancy number 21

PROJECT OUTLINE

Genomic alterations are major determinant of responses to (targeted) therapies in cancer. In fact, the best positive and negative predictors of responses to targeted therapies are alterations in kinases or their direct downstream effectors. To gain insight into resistance mechanisms to therapy and thus better tailor treatment, we are approaching this problem from two different angles. First we have transplanted tumors from mouse models of breast cancer and treated these tumors with a range of (targeted) therapies. Matched pre- and post treatment pairs of resistant and sensitive tumors have been full exon sequenced and are available for analysis. The goal is to detect genomic alterations associated with response to therapy. Second, we have acquired large panels of human tumors, on which we are currently performing kinase exon sequencing. More specifically, we are performing sequencing on 1) 400 samples from the NEO-ALTTO study to find alterations associated with resistance to HER2 targeted therapies; 2) at least 200 colorectal samples and 300 breast cancers (triple negatives and invasive lobular carcinomas) to detect alterations frequently occurring in these patient populations. A very strong feature of all these datasets is that matched controls are available to ensure high accuracy in variant calling. The successful candidates will work closely with the biological groups to develop computational approaches for the detection of mutations and copy number alterations associated with specific cancer subtypes as well as therapy response in human and mouse model-derived tumors.

CANDIDATE REQUIREMENTS – EDUCATION AND EXPERIENCE

We are seeking highly motivated Postdoc and PhD candidates with a degree in bioinformatics or a mathematical discipline with a strong cancer biological interest. Applicants should either have strong modeling/applied statistics skills or strong documented experience in analyzing high-throughput sequencing data. In addition, we strongly value experience in one or more of the following: sequence analysis, machine learning, applied statistics and R, computer science and expression analysis. The candidate also needs to be proficient in a programming language such as Java, Perl or Python, and be comfortable with Linux systems. Fluency in spoken and written English is a strong requirement.

LOCATION

The project will employ the complementary expertise and tools of three groups participating in the Cancer Systems Biology Center (csbc.nki.nl) at the Netherlands Cancer Institute, Amsterdam: Rene Bernards (Molecular Carcinogenesis), Jos Jonkers (Mouse Models for Breast Cancer) and Lodewyk Wessels (Computational Biology). The positions are primarily embedded within the Bioinformatics and Statistics Group (Wessels) (bioinformatics.nki.nl) at the Netherlands Cancer Institute, Amsterdam.

EMPLOYMENT CONDITIONS

The successful candidate will be employed by the Netherlands Cancer Institute. Postdocs will be appointed for a period of 3 years. The gross salary per month will be from € 3.200,- to € 4.095,- according to the FWG-function group 55 or 60, depending on proven qualities and previous experience. PhDs will be employed by the Netherlands Cancer Institute for a period of 4 years. The gross salary per month will be from € 2407,- to € 2964,- according to the PhD scales, depending on proven qualities and previous experience. The terms of employment will be in accordance with the CAO Ziekenhuizen (Collective Labour Agreement for Hospitals).

WANT MORE INFORMATION?

Please contact Dr. Lodewyk Wessels, tel. +31 20 512 7987 or e-mail: l.wessels@nki.nl. Also see bioinformatics.nki.nl and csbc.nki.nl for further information.

INTERESTED?

Your application letter (including your resume, a list of publications and the names and addresses of at least two persons that can be approached for references) can be attached before January 15, 2012 to the application form on our website (see link below). After dispatch of the form you will receive a reaction as soon as possible.

 http://www.nki.nl/Research/Career/Vacancies/Default/Postdoc_PhDs_Computational_Analysis_of_NGS_data_2011_157.htm

Looks like they made a mistake in the letter. Expiration date cant be right

2 PhD Students Tailored Treatment and systems biology of Chronic Heart Failure

Specificaties - (uitleg)

Functietypes	PhD positions
Wetenschappelijke discipline	Health
Uren	36.0 uren per week
Salaris	€ 2107 - € 2700
Werk-/denkniveau	Higher Professional Education +
Vacaturenummer	MR0329
Vertalingen	en

Solliciteer binnen 28 dagen op deze vacature

In Europe the prevalence of heart failure (HF) is about 10-20 in 1000 persons and the prevalence is rising due to the ageing European population. In persons over 75 years of age about 10% is affected. Despite major improvements in the last decennium, prognosis and quality of life of CHF patients is limited. One of the reasons is that response to pharmacological treatment varies between individuals. To investigate markers of treatment-response, 5000 HF patients will be followed in the BiOSTAT-CHF project for mortality, hospitalization and their quality of life. Demographic data, established biomarkers and new genomic and proteomic biomarkers will be combined in prognostic models to predict treatment-response. The BiOSTAT-CHF is an EU-funded project with collaborators from France, Greece, Germany, Italy, the Netherlands, Norway, Poland, and the UK (www.biostat-chf.eu). 
Within this project there are two vacant positions for PhD students.
1. The primary aim of the first project is the development of prognostic models for the response to pharmacological treatment by CHF patients. The prognostic models concern mortality and morbidity of the patients and will be based on well known statistical methods using established risk factors of CHF as well as new biomarkers identified from genome-wide and proteome-wide biomarker identification. The prognostic models will be developed from the primary BiOSTAT-CHF sample and will be validated in a well characterized second sample. 

2. The primary aim of the second project is the development of a systems biology approach to link the multidimensional clinical phenotypes of the CHF-patients and their outcome to genetic markers, gene transcription and translation levels in peripheral blood cells. Aim is to derive concise causal pathogenetic pathways that link the genetic and molecular data to the different CHF phenotypes and outcomes. For this project it is necessary to develop new statistical and bioinformatics methods.

Functie-eisen

We look for investigators with a master of science in medicine, biomedical/life sciences or (clinical) epidemiology (project 1) and investigators with a master of science in bioinformatics or mathematics/statistics (project 2). For both projects a very good command of the English language (spoken and in writing) is required because of frequent and intensive contacts with partners in the BiOSTAT-CHF project. Experience with clinical research and CHF is preferred but not a prerequisite. Candidates must be willing to travel to participating centers across Europe.

Arbeidsvoorwaarden

- A full time PhD position with the possibility to participate in the exiting BiOSTAT-CHF project and to write PhD-theses on developing future tools for personalized medicine and understanding molecular biological underpinnings of chronic heart failure.
- Employment by the AMC Medical Research foundation for a period of 12 months, with possible extension of the contract to 48 months.
- A gross salary will be € 2.107,00 per month in the first year, with an increase to the maximum of € 2.700,00 per month in the fourth year. In addition the AMR BV has an End of Year Bonus of 8.3% and a holiday payment of 8% of the gross yearly salary. 
- As a PhD candidate, you are entitled to follow courses provided by the AMC Graduate School.

Dienstverband: Temporary, 12 months, with possible extension of the contract to 48 months

PhD position Forensic Face Recognition

PhD position Forensic Face Recognition

Specificaties - (uitleg)

Locatie	Enschede
Functietypes	Promotieplaatsen
Wetenschappelijke discipline	Techniek
Uren	40.0 uren per week
Salaris	€ 2042 - € 2612
Werk-/denkniveau	Universitair
Vacaturenummer	187588
Vertalingen	en nl

Solliciteer binnen 88 dagen op deze vacature

When comparing a facial image from a crime scene with a police photograph, forensic experts pay attention to morphologic-anthropologic features, following a prescribed protocol. The support for the hypothesis that crime-scene and reference image originate from one individual is expressed in qualitative terms, such as “no support”, “limited sup-port”, “moderate support”, “strong support”, and “very strong support”. Presently a strong effort is being made to replace such a qualitative description by a likelihood ratio, which is a quantitative measure of evidential value that can support the judge in court to make an objective decision.

Biometric face recognition is an automated process, for example used in access control. It does not use morphologic-anthropologic features, but extracts and compares abstract features, resulting in a quantitative similarity score. If this is above a predetermined threshold, the compared faces are accepted as resulting from the same individual.

The NWO project Forensic Face Recognition combines the fields of forensic face comparison and biometric face recognition in order to develop a (partially) automated system for forensic facial comparison that quantifies the evidential value as a likelihood ratio thus supporting the court to make an objective decision. This will be realized by:
1. Automation of the current forensic morphological-anthropological practice.
2. Optimization of biometric face recognition for forensic applications.
3. Computation of likelihood ratios as quantitative evidential value from the above 2 systems.
Topics 1 and 2 will be addressed at the University of Twente. Topic 3 will be addressed at the University of Amsterdam.

The PhD student in Twente will do research on face recognition systems for the forensic domain. For this task, we are looking for a highly motivated researcher with an MSc degree in Electrical Engineering, Computer Science, Mathematics or a related topic, with adequate experimental and theoretical skills. You have knowledge of image processing, pattern recognition, and probability theory. Knowledge in more specific areas such as biometrics will be an advantage. Fluency in English is a requirement. An interview will be part of the selection procedure.

As PhD student, you will be appointed for a period of four years, at the end of which you must have completed a PhD thesis. During this period, you have the opportunity to broaden your knowledge by joining international exchange programs, to participate in national and international conferences and workshops, and to visit other research institutes and universities worldwide.
We offer a full-time PhD position in a dynamic and international environment. The duration of the contracts is four years. The gross salary will range from € 2.042,00 in the first year to € 2.612,00 per month in the fourth year. Additionally, the University of Twente provides excellent facilities for professional and personal development. In addition, we offer a holiday allowance (amounts to 8%) and an end-of-year bonus (amount to 8.3%) and a number of additional benefits. The labour agreements are in accordance with the CAO-NU for Dutch universities.

The University of Twente. We stand for life sciences and technology. High tech and human touch. Education and research that matter. New technology which drives change, innovation and progress in society. The University of Twente is the only campus university in the Netherlands; divided over six faculties we provide more than fifty educational programmes. The University of Twente has a strong focus on personal development and talented researchers are given scope for carrying out pioneering research.

In the Faculty of Electrical Engineering, Mathematics and Computer Science (EWI) is the place where these three disciplines shape Information and Communication Technology at the University of Twente. ICT is more than communication. In almost every product we use mathematics, electronics and computer technology are present, and ICT now contributes to all of societies' activities. It is no longer about gadgets that we do or do not want to use. The real integration of ICT is just beginning. What we need is more intelligence in our systems and improvement of their natural interaction with humans.

Found here: http://www.academictransfer.com/employer/UT/vacancy/12266/lang/nl/