Showing posts with label radiotherapy. Show all posts
Showing posts with label radiotherapy. Show all posts

Friday, 5 October 2012

VACANCY: 2 PhD-students biological treatment planning in radiotherapy and hyperthermia

Job AMR - 2 PhD-students biological treatment planning in radiotherapy and hyperthermia

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2 PhD-students biological treatment planning in radiotherapy and hyperthermia

Specifications - (explanation)
Location AMSTERDAM
Function typesResearch, Development, Innovation
Scientific fieldsHealth
Hours 36.0 hours per week
EducationUniversity Graduate
Job number 50054612-ACT-NL-031017
Translations
Apply for this job within 10 days

Job description

Hyperthermia is the application of elevated temperatures (41-45°C) to tumour tissue and is applied in combination with radiotherapy and/or chemotherapy to improve tumour control. Hyperthermia can be administered before, during or after radiotherapy/chemotherapy. The sensitizing effect of hyperthermia depends on both the realized tumor temperatures and the order of application. In the hyperthermia community there is no univocal policy about the sequence of radiotherapy and hyperthermia and different institutes apply different treatment schemes. This research project “Towards biological treatment planning in radiotherapy combined with hyperthermia to improve clinical outcome” aims to find the optimal order of application of radiotherapy and hyperthermia and thereby further improve the effectiveness of clinical hyperthermia. This will be investigated using sophisticated treatment planning computer models, in which the combined effect of hyperthermia and radiotherapy is modeled. For accurate modeling knowledge about biological tissue parameters is necessary, which will be obtained from cell line and animal experiments for combined treatments with radiotherapy and hyperthermia.

Requirements

For this project we have vacancies for two highly motivated PhD candidates. One of them will carry out the cell line and animal experiments and the other candidate will perform the computer modeling part of the project. Candidate 1 should have an MSc degree in (medical) biology or a related background. The candidate should have good command of English. Excellent communicative skills and the ability to work within a multidisciplinary research group are essential. The research will involve in vitro and animal experiments. Candidate 2 should have an MSc degree in physics or a related background. The candidate should have good command of English. Excellent communicative skills and the ability to work within a multidisciplinary research group are essential. Programming experience in C/C++ is recommended.

Conditions of employment

We offer a salary in line with the Collective Labour Agreement for University Medical Centres in the Netherlands (CAO UMC) with a range of added fringe benefits, such as an annual bonus of 8.3 %, holiday allowance, collective discounted rates for a number of insurances, an attractive bicycle scheme and/or public transport allowance and free parking!
The PhD candidates will be appointed in a full-time position (36 hours/week) for a period of four years and at the end each PhD candidate should have completed his/her PhD thesis. Gross monthly salary for PhD candidates range from € 2.141,- gross per month in the first year up to € 2.743,- gross per month in the fourth year.
For more information please contact dr. Petra Kok, Physicist/Computer Scientist, or dr. Klaas Franken, Radiobiologist +31 (0)20 56 64231.
Contract type: Temporary,

Organisation

AMR
The AMC is more than just a hospital. It is a world in which patient care, research and education are integrated, and in which people are always central. It is an academic world full of possibilities for talented individuals that are looking for a place where they can excel. Thinking big, daring to dream, cooperating internationally. And never letting yourself be put off by ‘It’s not possible’ or ’It won’t work anyway’. That is the AMC mentality.
AMC Medical Research supports financiers, project leaders and coworkers on clear, effective and Legal execution of medical research within the Academic Medical Center (AMC) third parties financed. It contains advising and guidance on project preparations, project services and staffing management.
As a temporary researcher you will be contracted by AMC Medical Research. The related AMC department which you will service is physically your workplace. Working directly with your supervisor and your colleagues within your expertise or institution will be the base for your content job, your daily management and your working environment. The AMC Medical Research BV general employment conditions are largely similar to those of Academic Medical Center.
More information about employer Academic Medical Center (AMC) on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/15717

Bron: http://www.academictransfer.com/employer/AMC/vacancy/15717/lang/en/

Thursday, 16 August 2012

VACANCY: Postdoc determining radiation dose distribution for radiotherapy

Job Erasmus MC - Postdoc for the department of Radiotherapy - Mathematical Optimization of Cancer Treatment

Postdoc for the department of Radiotherapy - Mathematical Optimization of Cancer Treatment

Specifications - (explanation)
Location Rotterdam, 3015 CE, The Netherlands
Function typesPostdoc positions, Research, Development, Innovation
Scientific fieldsHealth
Hours 36.0 hours per week
EducationDoctorate
Job number 27.03.12.TDdH
Translations
Apply for this job within 31 days

Job description

Approximately 50% of cancer patients is treated with radiotherapy. Success of a radiation treatment is largely determined by the quality of the delivered dose distribution. Doses should be very high in the tumor and as low as possible in surrounding healthy tissues, especially in vital radiation sensitive organs. Development of algorithms and procedures for design of individualized irradiation strategies (treatment plans) is a key research line of the department. Optimization of the patient’s dose distribution is a complex, non-convex and discrete mathematical problem with multiple objectives and constraints, and a patient anatomy that may change during the fractionated therapy. Not only the quality of the final dose distribution is important, but also optimization time, speed of daily dose delivery and required human interaction and workload. The selected candidate will participate in these investigations.

Requirements

  • PhD in operations research, numerical mathematics, or other relevant field;
  • Excellent programming skills (Python, C++, Matlab) for prototyping;
  • Ambitious and eager to take initiative;
  • Creative and excellent analytical skills;
  • Ability to work in a multi-disciplinary team.

Conditions of employment

We offer a full-time position for a period of 3 years in an exciting working environment, aiming at improvement of patient care. The salary will depend on relevant experience and the job conditions are according to the Collective Bargaining Agreement for University Medical Centers (CAO UMC).
Contract type: Temporary, 3 years

Organisation

Erasmus MC
Erasmus MC inspires and is challenging. You create your own opportunities in this University Medical Center. Whether it concerns learning and work or work and learning/continued learning. Each and every day our enthusiastic staff devote themselves to excellent, dedicated patient care, pioneering medical research and valued education. A conscious choice for work that matters, both nationally and internationally, at the heart of our multicultural home base ofRotterdam. Where attention to individual staff member comes naturally. Working from the heart. Together with people, for people: ‘patient-centered care’!

Department

Radiotherapy
The Erasmus MC-Daniel den Hoed Cancer Center encompasses one of the largest radiation oncology departments in Europe treating 5000 patients per year. The departement has a wide-ranged and internationally renowned research program. Physics is of major importance in the program and a large part of the 50 employees of the Medical Physics division is involved in research projects. The department is equipped with state-of-the-art technologies and an extensive R&D software framework. Apart from computer optimization, image-guided and adaptive treatment, robotic treatment, stereotactic treatment, and proton therapy are among the main research lines. The department participates in the Holland Particle Therapy Center (HollandPTC) project. Research is embedded in multi-disciplinary teams, consisting of radiation oncologists, (medical) physicists, radiation technologists, mathematicians, and computer scientists.

Additional information

For more information, please contact Prof.dr. B.J.M. Heijmen, head of physics, telephone (+31) (0) 10 7041304, e-mail: b.heijmen@erasmusmc.nl, Ir. S. Breedveld, project leader, telephone (+31) (0) 10 7042693, e-mail: s.breedveld@erasmusmc.nl, or Drs. M.J. de Bruin, head of operations, telephone (+31) (0) 10 7041480, e-mail: m.j.debruin@erasmusmc.nl. More information on the R&D program can be found at: www.ncbi.nlm.nih.gov/pubmed?term=heijmen%20b*.
More information about employer Erasmus MC (University Medical Center Rotterdam) on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/14749